Endocrine Abstracts

Women with Turner syndrome (TS) more frequently develop cardiovascular disease. Abnormal lipid metabolism is a well known risk factor for ischemic heart disease. Adiponectin as well as cytokines are useful tool in evaluation the fat tissue metabolism.The aim of the study was to evaluate the relationship between adiponectin, TNF-alpha, IL-6 and lipids in patients with TS.Patients and method: The study group consisted of 87 girls wit...

A 76-year obese women with diabetes mellitus t II, hypertension and urolithiasis was referred to our clinic for reason of high cortisol levels, which were detected in regional hospital, two days after cystoscopy and catheterization of right ureter. Cortisolemia was 35 μg% at 8.00 and 37 μg % at 22.00. Short dexamethasone test didn’t cause cortisol suppression (cortisolemia after 1 mg DXM was 27 μg %). After two days of dexamethasone (4×2 mg) blood cort...

UPD is a congenital disease characterized by the presence of two homologous chromosomes inherited from one parent in a diploid offspring. Its effects can be dramatic when the expression of essential genes is lacking. This is due to a phenomenon known as genomic imprinting where only one of the two chromosomal copies is active, depending on the parent of origin. Maternal uniparental disomy of the chromosome 14 (UPD 14 mat) is a rare disorder characterized by prenatal a...

Testosterone deficiency syndrome (TDS) may well contribute to a number of co-morbidities and multitude of symptoms which may affect one’s daily activities adversely. TDS prevalence in UK is 5:1000 and certain groups of patient’s are at higher risk of TDS, in particular elderly and patients with diabetes mellitus where 42% are known to have TDS. A retrospective audit was carried out to bench mark our practice in line with a publication of a recommended National/Europe...

Hypothyroidism is associated with higher risk of cardiovascular disease and increase of blood lipids. Previous evidence indicates that high dosage of levothyroxine could be cardiotoxic. There are fewer data describing mortality in subjects after treatment and stabilization of thyroid diseases and there are no data related to subjects with treated hypothyroidism. Aim of this study was to investigate correlations between the cardiovascular risk and metabolic status [Resting Ener...

Patient Z., 13 years old, transferres to the ICU with diagnosis: Diabetes mellitus newly diagnosed. Diabetic ketoacidotic coma II. Concomitant: Left-sided pneumonia.Objective: Cussmaul’s breath, 36/minute. Pulse 128/min. BP 100/60 mm Hg. Glycemia 30.4 mmol/l, ketones in urine: ++++. CBC, urine, biochemical analysis of blood had not any special features. In the dynamics of the phenomenon of increasing respiratory failure and falling hemodynamics, the...

A 68-year-old lady was admitted with constipation, epigastric pain, vomiting, occasional coffee ground emesis and melena. She had no chest pain, osmotic symptoms or weight changes. Past medical history was significant for peptic ulcer disease and she was not taking any medications apart from over the counter cod liver oil. She did not have diabetes or cardiovascular risk factors. Her sister had type 1 diabetes. Examination was remarkable for dehydration, mild tachycardia and m...

IntroductionTelemedicine is a useful tool for improving the availability of medical care, especially in the era of COVID-19. It is required to study the needs of the Russian population for telemedicine services for each specific disease.MethodsIn Russian Federation telemedicine consultations (TMC) have been legally allowed since 2018. According to the law, if the patient has not previously attended a face-to-...

BackgroundMost cases of primary hyperparathyroidism (PHPT) is caused by a single benign adenoma, multiple parathyroid neoplasms (MPN) occur less often in 10–15%, parathyroid carcinoma accounts for <3%. MPN can be sporadic or develop due to inherited genetic syndromes (most commonly multiple endocrine neoplasia syndrome type 1 (MEN-1) that usually manifest at a young age. The preoperative examination of patients with MPN is important for achievin...

Introduction: Heart Failure with Preserved Ejection Fraction (HFpEF) morbidity and mortality are increasing at an alarming rate in patients with prediabetes, insulin resistance and obesity. Vitamin D deficiency is associated with the risk of impaired glucose and lipid metabolism. All this substantiates the need to monitor the concentration vitamin D in women with this comorbid pathology. Aim of the study: is to investigate the severity of vitamin D defic...